SCHEMBL24701649

SCHEMBL24701649

CCC(C)(C)c1cc(-c2ccccc2)ncc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.45
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
PDGFRB P09619 1/20 0.41
KDR P35968 1/20 0.41
FLT3 P36888 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP3A4 P08684 2/20 0.40
NR3C1 P04150 2/20 0.40
KCNH2 Q12809 1/20 0.40
KMT2A Q03164 3/20 0.38
CYP11B1 P15538 2/20 0.38
CYP11B2 P19099 2/20 0.38
MEN1 O00255 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
IDO1 P14902 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25884943 0.88 LDHA (0.45) LDHANPC1RAB9APDGFRBKDR
SCHEMBL26261273 0.88 LDHA (0.49) LDHANPC1RAB9APDGFRBKDR
SCHEMBL23561587 0.87 LDHA (0.41) LDHANPC1RAB9APDGFRBKDR
SCHEMBL25885012 0.86 LDHA (0.46) LDHANPC1RAB9APDGFRBKDR
SCHEMBL25884863 0.83 LDHA (0.50) LDHANPC1RAB9APDGFRBKDR
SCHEMBL26000216 0.83 LDHA (0.38) LDHANPC1RAB9APDGFRBKDR
SCHEMBL26022380 0.80 TSHR (0.36) LDHANPC1RAB9ACYP3A4KMT2A
SCHEMBL26290575 0.78 LDHA (0.49) LDHANPC1RAB9APDGFRBKDR
SCHEMBL22674922 0.78 LDHA (0.41) LDHANPC1RAB9APDGFRBKDR
SCHEMBL26349165 0.77 LDHA (0.41) LDHANPC1RAB9APDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-05 US disclosed
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-08-10 US disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-15 US disclosed
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 LDHA 140/4885NPC1 1971/4885RAB9A 2516/4885
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF L1CAM, LEF1, PIEZO1 LDHA 190/4885NPC1 3614/4885RAB9A 1648/4885
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, CTCF, DNMT1 LDHA 1959/4885NPC1 3345/4885RAB9A 528/4885
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF CRY1, LEF1, PIEZO1 LDHA 314/4885NPC1 4075/4885RAB9A 834/4885
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 LDHA 37/4885NPC1 2961/4885RAB9A 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.