SCHEMBL24701774

SCHEMBL24701774

Cc1ccc(-c2cc(C)c(C3CCCCC3)cn2)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
ADK P55263 1/20 0.39
KDM1A O60341 1/20 0.39
PDE10A Q9Y233 1/20 0.39
PSMB5 P28074 1/20 0.38
ACVR2A P27037 1/20 0.38
TGFBR2 P37173 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
GRM5 P41594 3/20 0.36
SRC P12931 2/20 0.36
CNR1 P21554 1/20 0.35
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
CHRNA7 P36544 1/20 0.35
LDHA P00338 1/20 0.35
DGAT1 O75907 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24701700 0.98 KDM1A (0.40) NPC1RAB9AADKKDM1APDE10A
SCHEMBL24701784 0.88 LDHA (0.48) NPC1RAB9AGRM5ALOX5APFEN1
SCHEMBL18729485 0.86 LDHA (0.49) NPC1RAB9AGRM5ALOX5APFEN1
SCHEMBL25455749 0.77 S1PR1 (0.42) KDM1APSMB5DGAT1
SCHEMBL19373717 0.76 CYP1A2 (0.41) ALOX5APFEN1
SCHEMBL25884778 0.75 SSTR3 (0.39) NPC1RAB9AKDM1AACVR2ATGFBR2
SCHEMBL24105036 0.75 ALOX5AP (0.41) ALOX5APFEN1
SCHEMBL18790584 0.75 KDM1A (0.44) NPC1RAB9AKDM1ACHRNA7
SCHEMBL22994478 0.75 KDM1A (0.59) NPC1RAB9AKDM1AACVR2ATGFBR2
SCHEMBL17818428 0.74 NPC1 (0.42) NPC1RAB9AKDM1AACVR2ATGFBR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-05 US disclosed
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-15 US disclosed
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 NPC1 1971/4885RAB9A 2516/4885ADK 3648/4885
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF L1CAM, LEF1, PIEZO1 NPC1 3614/4885RAB9A 1648/4885ADK 3519/4885
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, CTCF, DNMT1 NPC1 3345/4885RAB9A 528/4885ADK 1520/4885
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 NPC1 2961/4885RAB9A 2090/4885ADK 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.