SCHEMBL24701700

SCHEMBL24701700

Cc1ccc(-c2cc(C)c(C3CCCC3)cn2)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ADK P55263 1/20 0.38
PDE10A Q9Y233 1/20 0.37
GRM5 P41594 7/20 0.37
ACVR2A P27037 1/20 0.36
TGFBR2 P37173 1/20 0.36
PSMB5 P28074 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.36
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
CHRNA7 P36544 1/20 0.36
LDHA P00338 1/20 0.36
DGAT1 O75907 1/20 0.35
SRC P12931 1/20 0.35
METAP2 P50579 1/20 0.34
METAP1 P53582 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24701774 0.98 NPC1 (0.41) KDM1ANPC1RAB9AADKPDE10A
SCHEMBL18729485 0.88 LDHA (0.49) NPC1RAB9AGRM5ALOX5APFEN1
SCHEMBL24701784 0.86 LDHA (0.48) NPC1RAB9AGRM5ALOX5APFEN1
SCHEMBL19373717 0.77 CYP1A2 (0.41) ALOX5APFEN1METAP2
SCHEMBL24105036 0.76 ALOX5AP (0.41) ALOX5APFEN1
SCHEMBL18790584 0.76 KDM1A (0.44) KDM1ANPC1RAB9ACHRNA7METAP2
SCHEMBL18729486 0.75 LDHA (0.45) NPC1RAB9AALOX5APFEN1LDHA
SCHEMBL25455749 0.75 S1PR1 (0.42) KDM1APSMB5DGAT1
SCHEMBL24701802 0.75 SYK (0.38) KDM1AACVR2ATGFBR2FEN1CHRNA7
SCHEMBL22795061 0.75 GRM5 (0.42) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-05 US disclosed
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-15 US disclosed
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309375-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 KDM1A 870/4885NPC1 1971/4885RAB9A 2516/4885
US-20230189629-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF L1CAM, LEF1, PIEZO1 KDM1A 1371/4885NPC1 3614/4885RAB9A 1648/4885
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, CTCF, DNMT1 KDM1A 177/4885NPC1 3345/4885RAB9A 528/4885
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 KDM1A 1284/4885NPC1 2961/4885RAB9A 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.