Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 3/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24706318 | 0.77 | CYP3A4 (0.55) | CYP3A4ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL24707363 | 0.76 | ALDH1A1 (0.45) | CYP3A4ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL24706317 | 0.75 | NPSR1 (0.49) | CYP3A4ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL24706330 | 0.72 | MAPT (0.42) | CYP3A4ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL24705914 | 0.72 | MAPT (0.43) | CYP3A4ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL24706992 | 0.71 | MAPT (0.44) | CYP3A4ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL1683410 | 0.70 | ULK1 (0.55) | RIPK1KITCDK8AXLPIK3CD | |
| SCHEMBL24130673 | 0.69 | ALDH1A1 (0.50) | CYP3A4ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL29375909 | 0.69 | CDK8 (0.49) | RIPK1KITCDK8AXLPIK3CD | |
| SCHEMBL24706027 | 0.69 | NPSR1 (0.43) | CYP3A4ALDH1A1HIF1ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220396553-A1 | NOVEL HYDRAZONE DERIVATIVE IN WHICH TERMINAL AMINE GROUP IS SUBSTITUTED WITH ARYL GROUP OR HETEROARYL GROUP, AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220396553-A1 | NOVEL HYDRAZONE DERIVATIVE IN WHICH TERMINAL AMINE GROUP IS SUBSTITUTED WITH ARYL GROUP OR HETEROARYL GROUP, AND USE THEREOF | AANAT, NAT1, HNMT | CYP3A4 215/4885ALDH1A1 402/4885HIF1A 909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.