Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MYOC | Q99972 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470643 | 0.88 | SCN4A (0.47) | MEN1KMT2AKDM4ESRD5A2RAB9A | |
| SCHEMBL27724976 | 0.80 | MEN1 (0.58) | MEN1KMT2AKDM4ESRD5A2RAB9A | |
| SCHEMBL28070177 | 0.78 | LMNA (0.44) | MEN1KMT2AKDM4ESRD5A2RAB9A | |
| SCHEMBL6246258 | 0.77 | SRD5A2 (0.58) | MEN1KMT2AKDM4ESRD5A2RAB9A | |
| SCHEMBL28335276 | 0.76 | MEN1 (0.50) | MEN1KMT2AKDM4ESRD5A2RAB9A | |
| SCHEMBL2891270 | 0.75 | MAPT (0.41) | MEN1KMT2AKDM4EMAPTNPSR1 | |
| SCHEMBL24168164 | 0.75 | HSPB1 (0.51) | MEN1KMT2AKDM4ESRD5A2RAB9A | |
| SCHEMBL3552198 | 0.75 | ALDH1A1 (0.59) | MEN1KMT2AKDM4ESRD5A2RAB9A | |
| SCHEMBL1890124 | 0.75 | ALDH1A1 (0.59) | MEN1KMT2AKDM4ESRD5A2RAB9A | |
| SCHEMBL28227048 | 0.75 | HSPB1 (0.51) | MEN1KMT2AKDM4ESRD5A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085388-A | Synthesis method for sorafenib intermediate | HEFEI HUAFANG PHARMACEUTICAL SCIENCES & TECHNOLOGY CO LTD | 2015-11-25 | — | — | CN | disclosed |
| CN-104557688-A | Synthetic method for Sorafenib intermediate and synthetic method for compound A used for synthesizing Sorafenib intermediate | ASYMCHEM LAB TIANJIN CO LTD | 2015-04-29 | — | — | CN | disclosed |