SCHEMBL2470872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2469050	0.89	MAPT (0.46)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2472364	0.83	GABRA5 (0.43)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2468947	0.83	MAPT (0.46)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2470840	0.82	GABRA5 (0.43)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2472255	0.82	PTGS2 (0.52)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2470784	0.82	MAPK14 (0.42)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2472135	0.81	GABRA5 (0.44)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2470549	0.78	GABRA5 (0.42)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2474321	0.77	MAPT (0.41)	MAPTTDP1L3MBTL1PTGS1PTGS2
	SCHEMBL2469049	0.77	GABRA5 (0.42)	MAPTTDP1L3MBTL1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.