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Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2469221

Cc1cn([C@@H]2O[C@H](C(O)OP(O)(=S)OC3(O)C(O)[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3CO)C(O)C2O)c(=O)[nH]c1=O.N

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ ALB P02768 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ ADRA1A P35348 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ TYMP P19971 6/20 0.39
▸ TK2 O00142 2/20 0.37
▸ P2RY2 P41231 1/20 0.37
▸ TK1 P04183 1/20 0.37
▸ DNPH1 O43598 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL932885 0.99 ALDH1A1 (0.40) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL932061 0.82 LMNA (0.43) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL65561 0.81 ALDH1A1 (0.41) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL933232 0.81 ALDH1A1 (0.41) ALDH1A1LMNAALBPOLBADRA1A
Ammonia Solution, Strong SCHEMBL2470901 0.80 NT5E (0.39) LMNAALBP2RY2TK1
SCHEMBL16495059 0.79 NT5E (0.39) LMNAALBP2RY2TK1
SCHEMBL2470818 0.78 SLC28A1 (0.43) P2RY2
SCHEMBL16495245 0.78 SLC28A1 (0.43) P2RY2
SCHEMBL16495246 0.78 SLC28A1 (0.43) P2RY2
SCHEMBL11404005 0.78 DNPH1 (0.45) ALDH1A1LMNAALBPOLBADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2370451-A2 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS Chiralgen, Ltd. (JP) 2011-10-05 — — EP disclosed
WO-2010064146-A2 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS CHIRALGEN, LTD. (JP) 2010-06-10 — — WO disclosed