Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31141400 | 0.98 | SIGMAR1 (0.52) | SIGMAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5698242 | 0.82 | MAPT (0.42) | SIGMAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL146714 | 0.77 | NPC1 (0.56) | SIGMAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2670562 | 0.75 | ALDH1A1 (0.45) | SIGMAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14223264 | 0.75 | SIGMAR1 (0.43) | SIGMAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10800951 | 0.75 | KEAP1 (0.44) | SIGMAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8996705 | 0.75 | ALOX5 (0.45) | MEN1KMT2AALOX5POLBMAPT | |
| SCHEMBL6182088 | 0.75 | MAPT (0.36) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL6408693 | 0.75 | ALDH1A1 (0.38) | SIGMAR1ALOX5HTR3EHTR3BHTR3A | |
| SCHEMBL6224361 | 0.72 | NPC1 (0.50) | SIGMAR1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1180311-A | Use of 'alpha' 1L agonists in treatment of incontinence | BOEHRINGER INGELHEIM KG (DE) | 1998-04-29 | — | — | CN | claimed |
| WO-2022257581-A1 | A CLASS OF IMIDAZOLIDINOPYRIMIDONE COMPOUNDS AND USE THEREOF IN TREATMENT OF HSCLPP-MEDIATED DISEASES | 四川大学 | 2022-12-15 | — | — | WO | disclosed |
| CN-1491216-A | Novel alkylphenylimidazolidine derivatives for the treatment of urinary incontinence | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-04-21 | — | — | CN | disclosed |
| CN-1471514-A | Novel M-amino-phenylimino-imidazolidone derivatives for treating urinary incontinence | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-01-28 | — | — | CN | disclosed |