SCHEMBL24709397

SCHEMBL24709397

CC(C)(C)OC(=O)CN1CC[C@@](C)(C(=O)O)C1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.34
RORC P51449 1/20 0.34
PLA2G10 O15496 2/20 0.33
PLA2G5 P39877 2/20 0.33
S1PR1 P21453 2/20 0.32
S1PR5 Q9H228 1/20 0.31
DRD2 P14416 2/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
CACNA1H O95180 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30
WNT1 P04628 1/20 0.30
GSK3B P49841 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14671153 0.80 RORC (0.35) RORCPLA2G10PLA2G5DRD2CYP4F2
SCHEMBL31531412 0.79 PLA2G10 (0.39) RORCPLA2G10PLA2G5DRD2CACNA1H
SCHEMBL28509736 0.78 DRD2 (0.36) RORCPLA2G10PLA2G5DRD2CACNA1H
SCHEMBL18063233 0.77 RORC (0.34) RORCPLA2G10PLA2G5CYP4F2CYP4A11
SCHEMBL13092962 0.75 RORC (0.35) RORCPLA2G10PLA2G5DRD2CYP4F2
SCHEMBL20631256 0.74 PLA2G10 (0.38) RORCPLA2G10PLA2G5DRD2CACNA1H
SCHEMBL3799622 0.74 PLA2G10 (0.41) PLA2G10PLA2G5CACNA1HWNT1GSK3B
SCHEMBL3470166 0.74 PLA2G10 (0.41) PLA2G10PLA2G5CACNA1HWNT1GSK3B
SCHEMBL27147241 0.74 PLA2G10 (0.41) PLA2G10PLA2G5CACNA1HWNT1GSK3B
SCHEMBL25728385 0.74 HSD17B10 (0.37) PLA2G10PLA2G5CACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230271917-A1 AMINO ACIDS PARABILIS MEDICINES, INC. 2023-08-31 US disclosed
WO-2022261257-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2022-12-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271917-A1 AMINO ACIDS NPPA, QPCTL, PTMS FFAR3 3058/4885RORC 3965/4885PLA2G10 1483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.