SCHEMBL18063233

SCHEMBL18063233

COCC1(C(=O)O)CCN(CC(=O)OC(C)(C)C)C1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
KDM1A O60341 1/20 0.31
DGAT1 O75907 1/20 0.31
PLA2G10 O15496 1/20 0.30
PLA2G5 P39877 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2472422 0.88 CYP4F2 (0.35) RORCCYP4F2CYP4A11DGAT1PLA2G10
SCHEMBL13092962 0.82 RORC (0.35) RORCCYP4F2CYP4A11KDM1APLA2G10
SCHEMBL31231163 0.79 CYP4F2 (0.43) RORCCYP4F2CYP4A11
SCHEMBL3736290 0.79 CYP4F2 (0.43) RORCCYP4F2CYP4A11
Hydrochloric Acid SCHEMBL3788428 0.78 CYP4F2 (0.42) RORCCYP4F2CYP4A11
SCHEMBL24709397 0.77 FFAR3 (0.34) RORCCYP4F2CYP4A11PLA2G10PLA2G5
SCHEMBL12193843 0.76 RORC (0.33) RORC
SCHEMBL607839 0.76 USP2 (0.46) CYP4F2CYP4A11
SCHEMBL14671153 0.75 RORC (0.35) RORCCYP4F2CYP4A11KDM1APLA2G10
SCHEMBL2472488 0.74 SMN1; SMN2 (0.37) CYP4F2CYP4A11OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2017-10-05 US claimed
US-20160272733-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECHNOLOGY LTD. (CN) 2016-09-22 US claimed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
US-10208146-B2 Catalyst component for olefin polymerization and application thereof BEIJING LIHE TECHNOLOGY LTD. (CN) 2019-02-19 US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 US disclosed
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2017-10-05 US disclosed
US-20160272733-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECHNOLOGY LTD. (CN) 2016-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208146-B2 Catalyst component for olefin polymerization and application thereof TEC, ETFA, TECR RORC 3744/4885CYP4F2 31/4885CYP4A11 171/4885
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B RORC 3143/4885CYP4F2 148/4885CYP4A11 660/4885
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF TEC, ETFA, TECR RORC 3744/4885CYP4F2 31/4885CYP4A11 171/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 RORC 2809/4885CYP4F2 251/4885CYP4A11 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.