Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.66 |
| ▸ | SHBG | P04278 | 2/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 3/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259619 | 0.91 | AR (0.67) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6905409 | 0.91 | AR (0.67) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6836638 | 0.88 | AR (0.71) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL7706417 | 0.88 | AR (0.71) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24711298 | 0.86 | LMNA (0.53) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL4265902 | 0.86 | AR (0.61) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24102607 | 0.86 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24102603 | 0.86 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6841921 | 0.86 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6241583 | 0.86 | AR (0.74) | ARSHBGSERPINA6SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257895-A1 | INTERMEDIATE FOR PREPARING FULVESTRANT AND PREPARATION METHOD THEREFOR | 上海弼领生物技术有限公司 | 2022-12-15 | — | — | WO | disclosed |