Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19188023 | 0.82 | NAMPT (0.60) | NAMPTMCHR1CTSCPDE4BALDH1A1 | |
| SCHEMBL24724942 | 0.81 | ESRRG (0.45) | CYP2C9CCR1ALDH1A1LMNAMAPT | |
| SCHEMBL10291524 | 0.81 | NAMPT (0.59) | NAMPTMCHR1CCR1ALDH1A1LMNA | |
| SCHEMBL4198757 | 0.80 | NAMPT (0.65) | NAMPTADAMTS5ALDH1A1LMNAMAPT | |
| SCHEMBL6245254 | 0.79 | NAMPT (0.64) | NAMPTADAMTS5ALDH1A1LMNAMAPT | |
| SCHEMBL21565632 | 0.78 | CYP2C9 (0.50) | CYP2C9CCR1ALDH1A1LMNAMAPT | |
| SCHEMBL24933097 | 0.77 | NAMPT (0.49) | NAMPTCYP2C9ALDH1A1LMNAKCNH2 | |
| SCHEMBL25443738 | 0.74 | ADAMTS5 (0.43) | ADAMTS5CCR1KCNH2HRH3 | |
| SCHEMBL11445595 | 0.74 | MCHR1 (0.55) | NAMPTMCHR1ALDH1A1LMNA | |
| SCHEMBL9667339 | 0.74 | HDAC8 (0.54) | NAMPTCYP2C9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232195-A2 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-11-03 | — | — | WO | disclosed |