Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30735881 | 0.81 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL30735672 | 0.80 | ALDH1A1 (0.33) | CYP3A4ALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL30735764 | 0.80 | ALDH1A1 (0.33) | CYP3A4ALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL30735767 | 0.77 | KIF11 (0.40) | HPGDSLC6A2NPC1RAB9A | |
| SCHEMBL13647384 | 0.75 | ADRA2A (0.49) | CYP3A4ALDH1A1SIGMAR1ADRB2HTR1A | |
| SCHEMBL30735648 | 0.75 | RXRA (0.33) | OPRM1APP | |
| SCHEMBL30735516 | 0.73 | ESR1 (0.40) | ALDH1A1KDM4EESR2SLC6A2SLC6A3 | |
| SCHEMBL30735679 | 0.70 | SIGMAR1 (0.33) | SIGMAR1ADRA2A | |
| SCHEMBL6733562 | 0.67 | CA1 (0.79) | CYP3A4ALDH1A1KDM4EESR2NPC1 | |
| SCHEMBL197522 | 0.67 | CA1 (0.79) | CYP3A4ALDH1A1KDM4EESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430636-A | Chiral spiro phosphoramide compound and preparation method and application thereof | 南开大学 | 2024-01-23 | — | — | CN | disclosed |