Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776289 | 0.81 | CES2 (0.40) | CES2CES1MAPK1TSHRESR1 | |
| SCHEMBL1029288 | 0.81 | CES2 (0.40) | CES2CES1MAPK1TSHRESR1 | |
| SCHEMBL1719721 | 0.77 | TSHR (0.59) | CES2CES1MAPK1TSHRESR1 | |
| SCHEMBL16322420 | 0.75 | MAPK1 (0.38) | CES2CES1MAPK1TSHRESR1 | |
| SCHEMBL4582621 | 0.75 | ESR1 (0.57) | CES2CES1MAPK1TSHRESR1 | |
| SCHEMBL7198377 | 0.75 | TSHR (0.57) | CES2CES1MAPK1TSHRESR1 | |
| SCHEMBL29774130 | 0.75 | CES2 (0.41) | CES2CES1MAPK1TSHRESR1 | |
| Alcohol SCHEMBL28160506 | 0.73 | SMN1; SMN2 (0.50) | MAPK1TSHRESR1HTTCA1 | |
| SCHEMBL522175 | 0.73 | TSHR (0.61) | MAPK1TSHRESR1HTTCA1 | |
| SCHEMBL28334716 | 0.73 | CES2 (0.39) | CES2CES1MAPK1TSHRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041882-A1 | METHODS FOR SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | XENOPORT, INC. (US) | 2010-02-18 | — | — | US | claimed |
| US-7662987-B2 | Oxidation of 1-acyl alkyl compound under anhydrous condition | XENOPORT, INC. (US) | 2010-02-16 | — | — | US | claimed |
| US-20050070715-A1 | Methods for synthesis of acyloxyalkyl compounds | ARBOR PHARMACEUTICALS, LLC | 2005-03-31 | — | — | US | claimed |
| WO-2005010011-A2 | METHODS OF SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | XENOPORT, INC. (US) | 2005-02-03 | — | — | WO | claimed |
| US-20230145397-A1 | ION-CONDUCTIVE POLYMERIC MATERIALS AS ELECTROLYTES FOR FUEL CELLS | ENERGAO, INC. | 2023-05-11 | — | — | US | disclosed |
| WO-2021194588-A1 | ION-CONDUCTIVE POLYMERIC MATERIALS AS ELECTROLYTES FOR FUEL CELLS | ENERGAO, INC. (US) | 2021-09-30 | — | — | WO | disclosed |
| EP-2588502-B1 | POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION | NOURYON CHEMICALS INT BV (NL) | 2021-03-31 | — | — | EP | disclosed |
| EP-2400515-B1 | PROCESS FOR MANUFACTURING ELECTRET, AND ELECTROSTATIC INDUCTION-TYPE CONVERSION ELEMENT | ASAHI GLASS CO LTD (JP) | 2018-01-24 | — | — | EP | disclosed |
| EP-2400516-B1 | PROCESS FOR MANUFACTURING ELECTRET, AND ELECTROSTATIC INDUCTION-TYPE CONVERSION ELEMENT | ASAHI GLASS CO LTD (JP) | 2016-06-08 | — | — | EP | disclosed |
| US-9353057-B2 | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof | XENOPORT, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2250143-B1 | METHOD FOR THE ENZYMATIC KINETIC RESOLUTION OF ACYLOXYALKYL THIOCARBONATES USED FOR THE SYNTHESIS OF ACYLOXYALKYL CARBAMATES | XENOPORT INC (US) | 2016-04-20 | — | — | EP | disclosed |
| US-8987391-B2 | Polymerization process with in-situ initiator formation | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2015-03-24 | — | — | US | disclosed |
| EP-0623597-B1 | Pyridine derivatives, with potassium channel opening activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0802187-A1 | Hydroxypyridine derivatives, their production and their pharmaceutical use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0623597-A1 | Pyridine derivatives, with potassium channel opening activity | Takeda Chemical Industries, Ltd. (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-4008175-A | Organic acid anhydride-peroxydicarbonate composition | PPG INDUSTRIES, INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3985720-A | Polymerization of ethylenically unsaturated monomer employing a catalyst system comprising dialkylpyrocarbonate, organic acid anhydride, alkaline reagent and H2 O2 | PPG INDUSTRIES, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3978032-A | ALKALINE BUFFER, ANHYDRIDE, PERACID, ALKYL HALOFORMATE | PPG INDUSTRIES, INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145397-A1 | ION-CONDUCTIVE POLYMERIC MATERIALS AS ELECTROLYTES FOR FUEL CELLS | PFKFB3, PFKFB2, PFKFB4 | CES2 582/4885CES1 2027/4885MAPK1 1095/4885 |
| US-20050070715-A1 | Methods for synthesis of acyloxyalkyl compounds | AADAC, CYP2D6, CYP3A7 | CES2 14/4885CES1 56/4885MAPK1 2961/4885 |
| US-20100041882-A1 | METHODS FOR SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | AADAC, CYP2D6, CYP3A7 | CES2 14/4885CES1 56/4885MAPK1 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.