SCHEMBL24718702

SCHEMBL24718702

CCOP(OCC)N(C(C)C)P(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
LTA4H P09960 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29745776 0.85 LTA4H (0.31) LTA4H
SCHEMBL18473590 0.82
SCHEMBL29745774 0.82 CYP3A4 (0.32) ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL2233775 0.79 TDP1 (0.39) TSHRALDH1A1LMNATP53SMN1; SMN2
SCHEMBL13136018 0.74 LMNA (0.30) LMNA
SCHEMBL24718701 0.73 CYP3A4 (0.31)
SCHEMBL17828677 0.72 PGR (0.31)
SCHEMBL17828674 0.71 PGR (0.30)
SCHEMBL18840105 0.71 PGR (0.30)
SCHEMBL911476 0.71 CYP3A4 (0.39) TSHRLTA4HALDH1A1TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220241764-A1 CATALYST COMPOSITION AND PROCESS FOR OLIGOMERIZATION OF ETHYLENE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220241764-A1 CATALYST COMPOSITION AND PROCESS FOR OLIGOMERIZATION OF ETHYLENE XRN2, XRCC6, TRRAP TSHR 105/4885LTA4H 3117/4885ALDH1A1 4857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.