Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.61 |
| ▸ | CKS1B | P61024 | 1/20 | 0.52 |
| ▸ | SKP1 | P63208 | 1/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601155 | 0.85 | DPP4 (0.63) | WNT3ACKS1BSKP1SKP2FGFR3 | |
| SCHEMBL24721149 | 0.82 | WNT3A (0.55) | WNT3ACKS1BSKP1SKP2FGFR3 | |
| SCHEMBL12377892 | 0.82 | AOC3 (0.62) | WNT3ACKS1BSKP1SKP2AOC3 | |
| SCHEMBL13649187 | 0.77 | HRH3 (0.60) | KDRALDH1A1L3MBTL1RORCMGLL | |
| SCHEMBL12303103 | 0.76 | WNT3A (0.84) | WNT3AAOC3 | |
| SCHEMBL1724668 | 0.76 | WNT3A (1.00) | WNT3AAOC3 | |
| SCHEMBL12650860 | 0.76 | CKS1B (0.47) | CKS1BSKP1SKP2DRD2DRD4 | |
| SCHEMBL23601160 | 0.75 | GRM5 (0.50) | WNT3AGRIN2BDPP4 | |
| SCHEMBL23601169 | 0.75 | CKS1B (0.54) | WNT3ACKS1BSKP1SKP2DRD2 | |
| SCHEMBL16603476 | 0.75 | CNR2 (0.45) | WNT3ACKS1BSKP1SKP2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324866-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324866-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | DGKG, DGKB, DGKK | WNT3A 2896/4885CKS1B 329/4885SKP1 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.