Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.63 |
| ▸ | WNT3A | P56704 | 1/20 | 0.57 |
| ▸ | CKS1B | P61024 | 1/20 | 0.51 |
| ▸ | SKP1 | P63208 | 1/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | SMO | Q99835 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601169 | 0.87 | CKS1B (0.54) | DPP4WNT3ACKS1BSKP1SKP2 | |
| SCHEMBL23601160 | 0.87 | GRM5 (0.50) | DPP4WNT3AHPGDSMOGRM5 | |
| SCHEMBL23601161 | 0.87 | DPP4 (0.53) | DPP4WNT3AHPGDKDRHSD17B10 | |
| SCHEMBL24721026 | 0.85 | WNT3A (0.61) | DPP4WNT3ACKS1BSKP1SKP2 | |
| SCHEMBL12303103 | 0.84 | WNT3A (0.84) | WNT3AAOC3 | |
| SCHEMBL24721149 | 0.84 | WNT3A (0.55) | DPP4WNT3ACKS1BSKP1SKP2 | |
| SCHEMBL23601156 | 0.84 | RET (0.56) | DPP4WNT3ACKS1BSKP1SKP2 | |
| SCHEMBL15344195 | 0.83 | FYN (0.53) | TLR8TLR7CNR2 | |
| SCHEMBL23601153 | 0.83 | CNR2 (0.58) | TLR8TLR7CNR2 | |
| SCHEMBL1630859 | 0.80 | L3MBTL1 (0.58) | DPP4CKS1BSKP1SKP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |