Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601155 | 0.87 | DPP4 (0.63) | GRM5SMODPP4WNT3AHPGD | |
| SCHEMBL24721147 | 0.85 | PSEN1 (0.48) | SMOWNT3AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23601161 | 0.84 | DPP4 (0.53) | GRM5SMODPP4WNT3AHPGD | |
| SCHEMBL23601169 | 0.84 | CKS1B (0.54) | GRM5SMODPP4WNT3AHPGD | |
| SCHEMBL23601689 | 0.81 | SMO (0.57) | SMOHPGDMEN1HTTKMT2A | |
| SCHEMBL23601156 | 0.81 | RET (0.56) | DPP4WNT3A | |
| SCHEMBL15344195 | 0.80 | FYN (0.53) | — | |
| SCHEMBL23601153 | 0.80 | CNR2 (0.58) | SMN1; SMN2 | |
| SCHEMBL23601164 | 0.76 | KCNH2 (0.57) | — | |
| SCHEMBL12303103 | 0.75 | WNT3A (0.84) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |