Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24722876 | 0.87 | NPSR1 (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL24722746 | 0.87 | NPSR1 (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL24723423 | 0.85 | KDM4E (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL24722909 | 0.71 | DRD2 (0.36) | ADRA2AADRA2BADRA2CHTR1DHTR2A | |
| SCHEMBL26958319 | 0.69 | TIPARP (0.47) | HRH3HTR2AHTR2CHTR2B | |
| SCHEMBL691897 | 0.69 | HTR2A (0.49) | ADRA2AADRA2BADRA2CHTR1DHTR2A | |
| SCHEMBL26958226 | 0.68 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL26959683 | 0.68 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL2018650 | 0.68 | KDM4E (0.46) | ADRA2AADRA2BADRA2CHTR1DHTR2A | |
| SCHEMBL693038 | 0.68 | POLB (0.40) | HRH3ADRA2AADRA2BADRA2CHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022166920-A1 | PYRROLOPYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-08-11 | — | — | WO | disclosed |