SCHEMBL691897

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24722909	0.82	DRD2 (0.36)	HTR2AHTR2CHTR2BLMNAMEN1
	SCHEMBL693038	0.81	POLB (0.40)	HTR2AHTR2CHTR2BLMNAMEN1
	SCHEMBL2018650	0.81	KDM4E (0.46)	HTR2AHTR2CHTR2BLMNAMEN1
	SCHEMBL21278358	0.80	HTR2A (0.63)	HTR2AHTR2CHTR2BLMNAMEN1
	SCHEMBL13722074	0.77	HTR2C (0.55)	HTR2AHTR2CHTR2BLMNAMEN1
	SCHEMBL693333	0.76	HTT (0.43)	LMNAMEN1CYP3A4KMT2ACYP1A2
	SCHEMBL2015234	0.75	HTR2C (0.50)	HTR2AHTR2CHTR2BLMNAMEN1
	SCHEMBL692196	0.73	HTR2C (0.62)	HTR2AHTR2CHTR2BDRD2NOTUM
	SCHEMBL1350934	0.73	HTR2C (0.49)	HTR2AHTR2CHTR2BLMNAMEN1
	SCHEMBL2018571	0.71	HTR2C (0.40)	HTR2AHTR2CHTR2BLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.