Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | BCL6 | P41182 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24722876 | 1.00 | NPSR1 (0.33) | NPSR1HTR2AHTR2CHTR2BBCL6 | |
| SCHEMBL24723423 | 0.87 | KDM4E (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL24722751 | 0.87 | HRH3 (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL24722909 | 0.78 | DRD2 (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL24723123 | 0.77 | NPSR1 (0.34) | NPSR1HTR2AHTR2CHTR2B | |
| SCHEMBL691897 | 0.70 | HTR2A (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL22306381 | 0.70 | ALDH1A1 (0.39) | NPSR1 | |
| SCHEMBL2018650 | 0.69 | KDM4E (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL693038 | 0.69 | POLB (0.40) | HTR2AHTR2CHTR2B | |
| SCHEMBL14329347 | 0.68 | HTR2A (0.39) | HTR2AHTR2CHTR2BBCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022166920-A1 | PYRROLOPYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-08-11 | — | — | WO | disclosed |