Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313761 | 0.85 | ALDH1A1 (0.47) | LMNAL3MBTL1ALOX15 | |
| SCHEMBL8623162 | 0.84 | LMNA (0.64) | LMNAL3MBTL1FFAR1FFAR4PPARG | |
| SCHEMBL24723559 | 0.83 | HSD17B10 (0.44) | FFAR1ALOX15 | |
| SCHEMBL24723636 | 0.82 | LMNA (0.68) | LMNAL3MBTL1FFAR1FFAR4PPARG | |
| SCHEMBL11546821 | 0.82 | ALOX15 (0.48) | LMNAALOX15 | |
| SCHEMBL1513134 | 0.81 | ALOX15 (0.47) | ALOX15 | |
| SCHEMBL24723497 | 0.80 | LMNA (0.69) | LMNAL3MBTL1FFAR1FFAR4PPARG | |
| SCHEMBL12264540 | 0.79 | ALOX15 (0.44) | ALOX15 | |
| SCHEMBL12335889 | 0.78 | ALOX15 (0.49) | ALOX15 | |
| SCHEMBL5270144 | 0.78 | ALOX15 (0.49) | LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3737470-B1 | 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS | Celon Pharma Sa (PL) | 2022-12-14 | — | — | EP | disclosed |