Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PYGM | P11217 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666239 | 0.93 | MTNR1B (0.44) | MTNR1BHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL24724653 | 0.91 | ALDH1A1 (0.38) | MTNR1BALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL18666150 | 0.79 | MTNR1B (0.47) | MTNR1BALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL18666149 | 0.78 | ALDH1A1 (0.55) | MTNR1BALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL18666199 | 0.77 | DEGS1 (0.49) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL18666151 | 0.77 | MTNR1B (0.63) | MTNR1BALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL30567101 | 0.77 | MTNR1B (0.63) | MTNR1BALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL26267575 | 0.76 | MTNR1B (0.34) | MTNR1B | |
| SCHEMBL18666146 | 0.73 | ADRA2C (0.54) | MTNR1BALDH1A1LMNAPOLBTDP1 | |
| SCHEMBL29660113 | 0.73 | ADRA2C (0.54) | MTNR1BALDH1A1LMNAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232509-A1 | PCNA INHIBITORS AND EGFR INHIBITORS FOR CANCER TREATMENT | CITY OF HOPE (US) | 2022-11-03 | — | — | WO | disclosed |