Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24723933 | 0.91 | MTNR1B (0.38) | ALDH1A1KDM4EMAPTHPGDRECQL | |
| SCHEMBL18666150 | 0.87 | MTNR1B (0.47) | ALDH1A1KDM4EGFERMAPTHPGD | |
| SCHEMBL18666199 | 0.85 | DEGS1 (0.49) | ALDH1A1KDM4EGFERTAOK1PTPN1 | |
| SCHEMBL29660113 | 0.81 | ADRA2C (0.54) | ALDH1A1MTNR1BTAOK1ADRA2CMEN1 | |
| SCHEMBL18666146 | 0.81 | ADRA2C (0.54) | ALDH1A1MTNR1BTAOK1ADRA2CMEN1 | |
| SCHEMBL18666239 | 0.81 | MTNR1B (0.44) | ALDH1A1KDM4EMAPTHPGDRECQL | |
| SCHEMBL18666151 | 0.77 | MTNR1B (0.63) | ALDH1A1KDM4EMAPTRECQLMTNR1B | |
| SCHEMBL30567101 | 0.77 | MTNR1B (0.63) | ALDH1A1KDM4EMAPTRECQLMTNR1B | |
| SCHEMBL18666149 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTMTNR1BMEN1 | |
| SCHEMBL23099307 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EMAPTMTNR1BTAOK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232509-A1 | PCNA INHIBITORS AND EGFR INHIBITORS FOR CANCER TREATMENT | CITY OF HOPE (US) | 2022-11-03 | — | — | WO | disclosed |