Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 11/20 | 0.67 |
| ▸ | PTGER3 | P43115 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.44 |
| ▸ | PTGIR | P43119 | 4/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640837 | 0.88 | PTGFR (0.77) | PTGFRPTGER3MEN1THRBKMT2A | |
| SCHEMBL24340818 | 0.88 | PTGFR (0.77) | PTGFRPTGER3MEN1THRBKMT2A | |
| SCHEMBL11891872 | 0.88 | PTGFR (0.77) | PTGFRPTGER3MEN1THRBKMT2A | |
| SCHEMBL23353008 | 0.86 | PTGFR (0.63) | PTGFRPTGER3MEN1THRBKMT2A | |
| Enprostil SCHEMBL10746961 | 0.83 | PTGFR (0.64) | PTGFRPTGER3MEN1THRBKMT2A | |
| Enprostil SCHEMBL7107661 | 0.83 | PTGFR (0.64) | PTGFRPTGER3MEN1THRBKMT2A | |
| Enprostil SCHEMBL10746954 | 0.83 | PTGFR (0.64) | PTGFRPTGER3MEN1THRBKMT2A | |
| Enprostil SCHEMBL186877 | 0.83 | PTGFR (0.64) | PTGFRPTGER3MEN1THRBKMT2A | |
| Enprostil SCHEMBL1650019 | 0.83 | PTGFR (0.64) | PTGFRPTGER3MEN1THRBKMT2A | |
| SCHEMBL4303634 | 0.81 | PTGFR (1.00) | PTGFRPTGER3MEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281797-A1 | KEY INTERMEDIATE FOR SYNTHESIS OF PROSTAGLANDIN COMPOUND AND PREPARATION METHOD THEREOF | SHENZHEN CATALYS TECHNOLOGY CO., LTD (CN) | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281797-A1 | KEY INTERMEDIATE FOR SYNTHESIS OF PROSTAGLANDIN COMPOUND AND PREPARATION METHOD THEREOF | PTGES, PTGIS, PTGES2 | PTGFR 8/4885PTGER3 19/4885MEN1 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.