Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21377186 | 0.80 | ALDH1A1 (0.31) | NCF1 | |
| SCHEMBL5667084 | 0.77 | NCF1 (0.37) | NCF1SIGMAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL17282488 | 0.75 | NCF1 (0.36) | NCF1SIGMAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL41970 | 0.75 | NCF1 (0.65) | NCF1SIGMAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL20041189 | 0.75 | CYP1A2 (0.36) | NCF1CHRM2CHRM1CHRM3 | |
| SCHEMBL13206513 | 0.75 | TYMP (0.37) | — | |
| SCHEMBL25365 | 0.74 | — | — | |
| SCHEMBL11750040 | 0.74 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL203650 | 0.74 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL3574921 | 0.73 | HRH3 (0.36) | NCF1SIGMAR1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261504-A1 | DENDRIMER CONJUGATES AND METHODS OF USE THEREOF | Ashvattha Therapeutics, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |