SCHEMBL24727593

SCHEMBL24727593

CC1CCCCC2Oc3c(F)cccc3C12

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
CYP2D6 P10635 1/20 0.32
ADRA2A P08913 1/20 0.32
TERT O14746 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HRH1 P35367 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24727305 0.79 NOS3 (0.36) NOS3NOS1NOS2KDM4EGAA
SCHEMBL18536296 0.66 MEN1 (0.37) TAAR1CYP2D6ADRA2ATERTHTR2C
SCHEMBL24727407 0.65 HTR2C (0.33) NOS3NOS1NOS2ADRA2AHTR2C
SCHEMBL14070931 0.65 STS (0.39)
SCHEMBL24727177 0.64 ALDH2 (0.41) NOS3NOS1NOS2ADRA2AHTR2C
SCHEMBL14070956 0.63 STS (0.38)
SCHEMBL22474530 0.62 DRD2 (0.38) NOS3NOS1NOS2KDM4EGAA
SCHEMBL22474477 0.62 DRD2 (0.38) NOS3NOS1NOS2KDM4EGAA
SCHEMBL14197670 0.62 ADRA2A (0.50) TAAR1CYP2D6ADRA2ATERTHTR2C
SCHEMBL13498384 0.62 ADRA2A (0.50) TAAR1CYP2D6ADRA2ATERTHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074706-A1 DEUTERATED HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LG Display Co., Ltd. (KR) 2022-10-19 EP disclosed