SCHEMBL24727675

SCHEMBL24727675

Cc1ccc2c(c1)Cc1cc(F)ccc1-2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.49
CYP17A1 P05093 1/20 0.48
METAP1 P53582 2/20 0.47
ACHE P22303 4/20 0.42
MAPT P10636 3/20 0.41
RAB9A P51151 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7665011 0.88 PARP10 (0.46) PGRCYP17A1METAP1ACHEPARP10
SCHEMBL4897556 0.87 METAP1 (0.57) METAP1ACHEMAPTRAB9AKDM4E
SCHEMBL29633547 0.87 METAP1 (0.57) METAP1ACHEMAPTRAB9AKDM4E
SCHEMBL577480 0.87 PGR (0.49) PGRCYP17A1ACHEMAPTRAB9A
SCHEMBL29332473 0.82 METAP1 (0.53) METAP1ACHEMAPTRAB9AKDM4E
SCHEMBL21694418 0.80 METAP1 (0.52) METAP1ACHEMAPTRAB9AKDM4E
SCHEMBL9811056 0.80 PGR (0.49) PGRCYP17A1ACHEMAPTRAB9A
SCHEMBL23299014 0.79 PGR (0.44) PGRCYP17A1METAP1MAPTRAB9A
SCHEMBL19847335 0.79 HTR5A (0.45) PGRACHEPKMKIF11
SCHEMBL18568790 0.78 METAP1 (0.50) PGRMETAP1ACHEMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074706-A1 DEUTERATED HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LG Display Co., Ltd. (KR) 2022-10-19 EP disclosed