SCHEMBL24728778

SCHEMBL24728778

CCCCCCCCCCCCN(CCN)CCCCCCCCCC(=O)ON(CCCCCCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.43
KDM5A P29375 4/20 0.42
PHF8 Q9UPP1 2/20 0.42
KDM4C Q9H3R0 1/20 0.42
DGKA P23743 1/20 0.42
LMNA P02545 3/20 0.40
PAM P19021 2/20 0.39
MAPT P10636 2/20 0.38
MAPK1 P28482 1/20 0.38
TSHR P16473 1/20 0.37
ICMT O60725 1/20 0.37
ALB P02768 1/20 0.37
ALDH1A1 P00352 1/20 0.36
NAAA Q02083 1/20 0.36
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728573 0.89 DNM1 (0.46) DNM1KDM5APHF8KDM4CDGKA
SCHEMBL9249062 0.89 DNM1 (0.46) DNM1DGKALMNAPAMTSHR
SCHEMBL16027624 0.87 DNM1 (0.47) DNM1DGKALMNAPAMMAPT
SCHEMBL28657236 0.87 DGKA (0.53) DNM1DGKALMNAPAMMAPT
SCHEMBL31721661 0.86 DNM1 (0.44) DNM1KDM5APHF8KDM4CDGKA
SCHEMBL24729120 0.86 DNM1 (0.44) DNM1KDM5APHF8KDM4CDGKA
SCHEMBL25288794 0.86 DNM1 (0.44) DNM1KDM5APHF8KDM4CDGKA
SCHEMBL24728694 0.86 DNM1 (0.44) DNM1KDM5APHF8KDM4CDGKA
SCHEMBL31721549 0.86 DNM1 (0.44) DNM1KDM5APHF8KDM4CDGKA
SCHEMBL2044963 0.86 DNM1 (0.46) DNM1DGKALMNAPAMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022168085-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-08-11 WO disclosed