Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25140419 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1KDM4EPOLBCYP3A4HPGD | |
| SCHEMBL13034155 | 0.79 | MMP2 (0.54) | ALDH1A1KDM4ELMNAPOLBL3MBTL1 | |
| SCHEMBL13034141 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNACYP3A4MMP2 | |
| SCHEMBL27752252 | 0.78 | MRGPRX4 (0.47) | ALDH1A1KDM4ELMNAL3MBTL1CYP3A4 | |
| SCHEMBL10356766 | 0.76 | MEN1 (0.41) | ALDH1A1KDM4ELMNACYP3A4MMP2 | |
| SCHEMBL13034125 | 0.75 | MTNR1B (0.48) | ALDH1A1LMNAPOLBCYP3A4HPGD | |
| SCHEMBL25771725 | 0.75 | IDO1 (0.34) | ALDH1A1 | |
| SCHEMBL21705938 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNACYP3A4MMP2 | |
| SCHEMBL14255640 | 0.74 | IDO1 (0.58) | ALDH1A1KDM4EPOLBL3MBTL1GAA | |
| SCHEMBL20435047 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4EL3MBTL1CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061457-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 百奥泰生物制药股份有限公司 | 2023-04-20 | — | — | WO | disclosed |
| WO-2022253284-A1 | DRUG CONJUGATE AND USE THEREOF | 百奥泰生物制药股份有限公司 | 2022-12-08 | — | — | WO | disclosed |