Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24728848 | 0.81 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1MAPTTSHRCYP3A4 | |
| SCHEMBL13034120 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL13034128 | 0.78 | HSD17B10 (0.61) | ALDH1A1KMT2AMEN1HSD17B10 | |
| Hydrochloric Acid SCHEMBL4079309 | 0.78 | TAAR1 (0.44) | ALDH1A1MAPTKMT2AMEN1THRB | |
| SCHEMBL13034132 | 0.77 | ADRB2 (0.57) | SMN1; SMN2ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL11366139 | 0.77 | HTR6 (0.46) | HPGDPOLBHSD17B10 | |
| SCHEMBL25140472 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1MAPTCYP3A4KDM4E | |
| SCHEMBL1030014 | 0.73 | IDO1 (0.56) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10730178 | 0.73 | CYP3A4 (0.50) | SMN1; SMN2ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL20435047 | 0.73 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116911-A1 | ANTI-FRα ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 百奥泰生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023061457-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 百奥泰生物制药股份有限公司 | 2023-04-20 | — | — | WO | disclosed |