SCHEMBL2472916

SCHEMBL2472916

[O-][S+]1c2ccccc2Cc2c(Cl)cccc21.[O-][S+]1c2ccccc2Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.35
CYP2D6 P10635 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
PNMT P11086 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
TAAR1 Q96RJ0 1/20 0.32
AHR P35869 1/20 0.32
TSHR P16473 2/20 0.31
CYP1A2 P05177 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL151908 0.98 ADRA2A (0.36) ADRA2ACYP2D6ADRA2BADRA2CADRA1D
SCHEMBL158373 0.81 NOTUM (0.33) ADRA2AADRA2BADRA2CPNMT
SCHEMBL9160477 0.81 MAOA (0.39) TSHRCYP1A2LMNA
SCHEMBL36333 0.81 MAOA (0.39) TSHRCYP1A2LMNA
SCHEMBL10476775 0.81 MAOA (0.39) TSHRCYP1A2LMNA
SCHEMBL150109 0.81 AHR (0.33) AHRTSHRLMNA
Methacrylic Acid SCHEMBL16508011 0.80 FEN1 (0.31)
Ammonia Solution, Strong SCHEMBL1871983 0.79 MAOA (0.37) TSHRCYP1A2LMNA
Hydrochloric Acid SCHEMBL585839 0.79 MAOA (0.37) TSHRCYP1A2LMNA
SCHEMBL3657958 0.79 DRD2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2373717-A1 PHOTOCURABLE INTERPENETRATING POLYMER NETWORKS The Sherwin-Williams Company (US) 2011-10-12 EP disclosed
WO-2010074732-A1 PHOTOCURABLE INTERPENETRATING POLYMER NETWORKS THE SHERWIN-WILLIAMS COMPANY (US) 2010-07-01 WO disclosed
US-20100160480-A1 PHOTOCURABLE INTERPENETRATING POLYMER NETWORKS THE SHERWIN-WILLIAMS COMPANY (US) 2010-06-24 US disclosed
US-20100115874-A1 FLOORING SYSTEM INCLUDING A DRY GLUE PERGO (EUROPE) AB (SE) 2010-05-13 US disclosed
US-7678847-B2 Encapsulated structural adhesive APPLETON PAPERS INC. (US) 2010-03-16 US disclosed
US-7629394-B2 UV curable coating material of encapsulated water dispersed core material APPLETON PAPERS INC. (US) 2009-12-08 US disclosed
EP-1917317-A2 FLOORING SYSTEM INCLUDING A DRY GLUE Pergo (Europe) AB (SE) 2008-05-07 EP disclosed
US-20070197384-A1 UV curable coating material of encapsulated water dispersed core material APPLETON PAPERS INC. (US) 2007-08-23 US disclosed
WO-2007018736-A2 ENCAPSULATED STRUCTURAL ADHESIVE APPLETON PAPERS INC. (US) 2007-02-15 WO disclosed
US-20070021533-A1 Encapsulated structural adhesive APPLETON PAPERS INC. (US) 2007-01-25 US disclosed
WO-2007010409-A2 FLOORING SYSTEM INCLUDING A PREGLUE PERGO (EUROPE) AB (SE) 2007-01-25 WO disclosed