Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15339573 | 0.94 | GRIN2B (0.41) | GRIN2BCYP1A2CYP2C9CYP2C19GRIN1 | |
| SCHEMBL20731030 | 0.83 | CYP1A2 (0.38) | GRIN2BCYP1A2CYP2C9CYP2C19GRIN1 | |
| SCHEMBL23938080 | 0.83 | GRIN2B (0.43) | GRIN2BCYP1A2CYP2C9CYP2C19GRIN1 | |
| SCHEMBL15712202 | 0.79 | PKM (0.38) | GRIN2BCYP1A2CYP2C9CYP2C19GRIN1 | |
| SCHEMBL31403678 | 0.79 | KDM4C (0.40) | JAK1JAK2MAP3K5 | |
| SCHEMBL21783750 | 0.77 | MAP3K5 (0.39) | GRIN2BJAK1KDM1AGRM2JAK2 | |
| SCHEMBL21704227 | 0.77 | CCR1 (0.42) | CYP1A2CCR1CCR5CCR8 | |
| SCHEMBL21783643 | 0.77 | GRM2 (0.40) | GRIN2BJAK1KDM1AGRM2JAK2 | |
| SCHEMBL7859822 | 0.77 | HTR7 (0.42) | GRIN2BJAK1KDM1AGRM2JAK2 | |
| SCHEMBL21783728 | 0.76 | MAP3K5 (0.36) | GRIN2BJAK1KDM1AGRM2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | USP28, USP25, USP24 | GRIN2B 3388/4885CYP1A2 2136/4885CYP2C9 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.