SCHEMBL24730488

SCHEMBL24730488

CC(C)(O)c1cc(Cl)ccc1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ TMPRSS4 Q9NRS4 1/20 0.36
▸ DDR1 Q08345 1/20 0.36
▸ TSHR P16473 5/20 0.34
▸ MAPK1 P28482 3/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ HTT P42858 1/20 0.34
▸ ACLY P53396 1/20 0.33
▸ JAK2 O60674 1/20 0.33
▸ BTK Q06187 1/20 0.33
▸ PDK1 Q15118 2/20 0.33
▸ PDK2 Q15119 2/20 0.33
▸ PDK3 Q15120 2/20 0.33
▸ PDK4 Q16654 2/20 0.33
▸ HSD17B10 Q99714 2/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29464185 0.83 PGR (0.41) PGRMEN1KMT2ATSHRMAPK1
SCHEMBL19057574 0.83 PGR (0.41) PGRMEN1KMT2ATSHRMAPK1
SCHEMBL15143953 0.83 MAPK1 (0.38) MEN1KMT2ATMPRSS4DDR1TSHR
SCHEMBL16271595 0.79 SLC6A2 (0.36) MEN1KMT2ATMPRSS4DDR1TSHR
SCHEMBL29960430 0.79 DDR1 (0.36) MEN1KMT2ATMPRSS4DDR1TSHR
SCHEMBL11790248 0.78 TSHR (0.44) PGRMEN1KMT2ATSHRMAPK1
SCHEMBL30606438 0.78 KMT2A (0.46) MEN1KMT2ATSHRCYP3A4ALDH1A1
SCHEMBL16219704 0.78 SLC22A12 (0.37) PGRMEN1KMT2ATMPRSS4PDK2
SCHEMBL21102264 0.77 PGR (0.38) PGRMEN1KMT2ATSHRMAPK1
SCHEMBL9274255 0.77 ALOX15 (0.36) MEN1KMT2ATSHRMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 — — US disclosed
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 — — US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 — — US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 — — US disclosed
WO-2022213794-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-10-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF OCIAD1, OCIAD2, OSTC PGR 1932/4885MEN1 3934/4885KMT2A 3842/4885
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF OCIAD1, OCIAD2, EPCAM PGR 1884/4885MEN1 3324/4885KMT2A 2751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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