Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24398872 | 0.79 | CYP3A4 (0.41) | MAPK14GAAALDH1A1HTTMAPK1 | |
| SCHEMBL24730488 | 0.79 | PGR (0.41) | DDR1TMPRSS4GAAALDH1A1HTT | |
| SCHEMBL15143953 | 0.78 | MAPK1 (0.38) | DDR1TMPRSS4GAAALDH1A1HTT | |
| SCHEMBL16271595 | 0.75 | SLC6A2 (0.36) | DDR1TMPRSS4ALDH1A1HTTMAPK1 | |
| SCHEMBL12317693 | 0.72 | CA2 (0.37) | MAPK14ALDH1A1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL27334948 | 0.71 | DDR1 (0.40) | DDR1TMPRSS4GAAALDH1A1MAPK1 | |
| SCHEMBL30606438 | 0.70 | KMT2A (0.46) | ALDH1A1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL1410268 | 0.70 | TMPRSS4 (0.51) | DDR1TMPRSS4HTTMAPK1KDM4E | |
| SCHEMBL31193921 | 0.70 | TMPRSS4 (0.51) | DDR1TMPRSS4HTTMAPK1KDM4E | |
| SCHEMBL30298217 | 0.69 | KDM4E (0.40) | DDR1TMPRSS4GAAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |