Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.32 |
| ▸ | MGMT | P16455 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736511 | 0.67 | MAP4K4 (0.40) | HTTLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL5572109 | 0.62 | NR3C2 (0.41) | NR3C2HTTLMNAKDM4CMMP1 | |
| SCHEMBL5437592 | 0.62 | SMN1; SMN2 (0.39) | NR3C2HTTLMNAKDM4CMMP1 | |
| SCHEMBL5437601 | 0.62 | SMN1; SMN2 (0.39) | NR3C2HTTLMNAKDM4CMMP1 | |
| SCHEMBL28178459 | 0.61 | CYP1A2 (0.45) | HTTLMNAALDH1A1MAPTNOTUM | |
| SCHEMBL14495394 | 0.61 | P2RX7 (0.47) | NR3C2HTTKDM4CMMP1KDM5A | |
| SCHEMBL28406748 | 0.61 | HSPB1 (0.50) | MAPTKMT2ATDP1L3MBTL1 | |
| SCHEMBL20240814 | 0.60 | MAPT (0.43) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28317434 | 0.60 | KDM4E (0.45) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16914166 | 0.60 | POLB (0.34) | HTTLMNAALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787991-A1 | PYRROLOÝ2,3-c¨PYRIDINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2007-05-23 | — | — | EP | disclosed |