SCHEMBL2473142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3835165	0.94	CD274 (0.58)	CD274POLBHDAC1ALDH1A1GAA
	SCHEMBL2475817	0.92	HDAC1 (0.60)	CD274POLBHDAC1KMT2AKDM1A
	SCHEMBL1482637	0.91	CD274 (0.52)	CD274POLBHDAC1ALDH1A1GAA
	SCHEMBL2473832	0.91	HDAC1 (0.52)	CD274HDAC1ALDH1A1GAAHTT
	SCHEMBL2476742	0.88	HDAC1 (0.50)	CD274HDAC1ALDH1A1SMN1; SMN2KDM1A
	SCHEMBL2475736	0.88	HDAC1 (0.50)	CD274HDAC1HTTSMN1; SMN2MEN1
	SCHEMBL12249896	0.88	HTT (0.46)	CD274POLBHDAC1ALDH1A1BCL3
	SCHEMBL12199935	0.86	POLB (0.53)	POLBHDAC1ALDH1A1GAABCL3
	SCHEMBL3230045	0.85	CD274 (0.45)	CD274POLBHDAC1ALDH1A1KDM4E
	SCHEMBL2500464	0.85	SUCNR1 (0.47)	CD274POLBHDAC1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.