SCHEMBL2500464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2473832	0.94	HDAC1 (0.52)	SUCNR1HDAC1CD274MAPK1DRD2
	SCHEMBL3835165	0.90	CD274 (0.58)	SUCNR1HDAC1CD274POLBMAPK14
	SCHEMBL2475817	0.87	HDAC1 (0.60)	SUCNR1HDAC1CD274DRD2KMT2A
	SCHEMBL3225036	0.87	PDCD1 (0.46)	SUCNR1HDAC1CD274DRD2POLB
	SCHEMBL12199815	0.85	HDAC1 (0.46)	HDAC1MAPK1MEN1KMT2AHSD17B10
	SCHEMBL2473142	0.85	CD274 (0.54)	HDAC1CD274MEN1KMT2AKDM1A
	SCHEMBL2476742	0.84	HDAC1 (0.50)	SUCNR1HDAC1CD274DRD2KDM1A
	SCHEMBL2475736	0.84	HDAC1 (0.50)	SUCNR1HDAC1CD274DRD2MEN1
	SCHEMBL2473961	0.83	HDAC1 (0.53)	HDAC1CD274HDAC2HDAC8HDAC6
	SCHEMBL2480604	0.83	HDAC1 (0.58)	HDAC1KDM1AHDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.