Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221243 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNACRBNMMP2MMP9 | |
| SCHEMBL28864845 | 0.71 | SMN1; SMN2 (0.32) | SMN1; SMN2LMNACRBNMMP2MMP9 | |
| SCHEMBL29017521 | 0.71 | CRBN (0.31) | CRBN | |
| SCHEMBL1583554 | 0.71 | SMN1; SMN2 (0.32) | SMN1; SMN2LMNACRBNMMP2MMP9 | |
| SCHEMBL29110865 | 0.71 | CRBN (0.31) | CRBN | |
| SCHEMBL29138678 | 0.71 | CRBN (0.31) | CRBN | |
| SCHEMBL48327 | 0.71 | LMNA (0.36) | SMN1; SMN2LMNACRBNMMP2MMP9 | |
| SCHEMBL12189561 | 0.70 | CRBN (0.33) | CRBN | |
| SCHEMBL10647284 | 0.70 | — | — | |
| SCHEMBL24227250 | 0.70 | SMN1; SMN2 (0.31) | SMN1; SMN2LMNACRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1374911-B1 | AGENTS FOR MEASURING PYRIMIDINE METABOLIZABILITY | OTSUKA PHARMA CO LTD (JP) | 2013-10-16 | — | — | EP | claimed |
| CN-113166790-B | Methods and compositions for messenger RNA purification | 川斯勒佰尔公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-117916387-A | Compositions and methods for RNA affinity purification | 赛诺菲 | 2024-04-19 | — | — | CN | disclosed |
| CN-117402871-A | Method for purifying messenger RNA | 川斯勒佰尔公司 | 2024-01-16 | — | — | CN | disclosed |
| US-8883121-B2 | Oral preparation useful in measurement capacity to metabolize pyridine | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-1374911-B1 | AGENTS FOR MEASURING PYRIMIDINE METABOLIZABILITY | OTSUKA PHARMA CO LTD (JP) | 2013-10-16 | — | — | EP | disclosed |
| EP-1920786-B1 | ORAL PREPARATION FOR MEASURING PYRIMIDINE METABOLIC CAPACITY | OTSUKA PHARMA CO LTD (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-7666977-B2 | Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-02-23 | — | — | US | disclosed |
| WO-2008136842-A1 | POLY( CARBONATE-CO-UREA) COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008136841-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-11-13 | — | — | WO | disclosed |
| US-20080275209-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | GENERAL ELECTRIC COMPANY (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080275206-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | GENERAL ELECTRIC COMPANY (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080233048-A1 | Powder by mixing and pulverizing an isotope-labeled uracil, or metabolite labeled with an isotope of carbon atoms, oxygen atoms, or nitrogen atoms and mannitol; time required for the determination and number of measurements can be reduced, decreasing the burden on patients | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-09-25 | — | — | US | disclosed |
| EP-1920786-A1 | ORAL PREPARATION USEFUL IN MEASURING CAPACITY TO METABOLIZE PYRIDINE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-05-14 | — | — | EP | disclosed |
| US-20030068272-A1 | Preparation for determining pyrimidine metabolic capacity | OTSUKA PHARMACEUTICAL CO., LTD. | 2003-04-10 | — | — | US | disclosed |