SCHEMBL28864845

SCHEMBL28864845

CC1(I)CNC(=O)NC1=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 1/20 0.31
CRBN Q96SW2 1/20 0.31
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6221243 0.75 SMN1; SMN2 (0.34) SMN1; SMN2LMNACRBNMMP2MMP9
SCHEMBL1583554 0.71 SMN1; SMN2 (0.32) SMN1; SMN2LMNACRBNMMP2MMP9
SCHEMBL2473210 0.71 SMN1; SMN2 (0.32) SMN1; SMN2LMNACRBNMMP2MMP9
SCHEMBL10647284 0.70
SCHEMBL24227250 0.70 SMN1; SMN2 (0.31) SMN1; SMN2LMNACRBN
SCHEMBL4339901 0.68 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL887861 0.66
SCHEMBL8769135 0.66 ALDH1A1 (0.43) LMNAMMP2MMP9
SCHEMBL21031966 0.65 LMNA (0.44) LMNACRBNMMP2MMP9
SCHEMBL12189561 0.65 CRBN (0.33) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108495930-A Preparation method of brown fat cells 京都府公立大学法人 2018-09-04 CN disclosed