Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2478272 | 0.98 | MAPT (0.43) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL2477034 | 0.87 | ADRA2B (0.45) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL6271916 | 0.87 | MAPT (0.55) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL6270658 | 0.87 | MAOB (0.46) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL6272552 | 0.87 | HDAC4 (0.42) | GAAADRA2BHTR6HDAC4 | |
| SCHEMBL6273652 | 0.87 | MAPT (0.52) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL6743520 | 0.87 | MAPT (0.38) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL6269748 | 0.87 | BCHE (0.45) | MAPTKMT2ATDP1ADRA2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL6273889 | 0.86 | ADRA2B (0.44) | MAPTKDM4EMEN1LMNAGAA | |
| SCHEMBL6339193 | 0.86 | MAPT (0.44) | MAPTKDM4EMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558204-B1 | MEANS FOR COLOURING KERATIN FIBRES COMPRISING 2-AMINO-5-ETHYLPHENOL | Wella GmbH (DE) | 2011-10-12 | — | — | EP | claimed |
| US-7195649-B2 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | WELLA AG (DE) | 2007-03-27 | — | — | US | claimed |
| EP-1562540-B1 | N-ARYL-4,5-DIAMINOPYRAZOLS AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2006-08-30 | — | — | EP | claimed |
| EP-1116711-B1 | 2-aminoalkyl-1,4-diaminobenzene derivatives and dye composition containing these compounds | WELLA AG (DE) | 2005-12-14 | — | — | EP | claimed |
| EP-1562540-A1 | N-ARYL-4,5-DIAMINOPYRAZOLS AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | claimed |
| EP-1558204-A1 | MEANS FOR COLOURING KERATIN FIBRES COMPRISING 2-AMINO-5-ETHYLPHENOL | Wella Aktiengesellschaft (DE) | 2005-08-03 | — | — | EP | claimed |
| US-20050081312-A1 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2005-04-21 | — | — | US | claimed |
| US-20050011016-A1 | Means for colouring keratin fibres comprising 2-amino-5-ethylphenol | WELLA AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | US | claimed |
| US-6800097-B2 | FOR DYEING KERATIN FIBERS; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-05 | — | — | US | claimed |
| US-6780998-B2 | DEVELOPER-COUPLER SUBSTANCE COMBINATION HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-24 | — | — | US | claimed |
| WO-2004041225-A1 | MEANS FOR COLOURING KERATIN FIBRES COMPRISING 2-AMINO-5-ETHYLPHENOL | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | claimed |
| US-6685751-B2 | SUCH AS 2-((2-AMINO-PHENYLAMINO)-METHYL)-1,4-DIAMINOBENZENE; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | claimed |
| US-6602302-B1 | Mixtures of carbocyclic amines such as 2-((2-aminophenylamino) -methyl)-1,4-diaminobenzene, couplers and developers, having photostability, wash and colorfastness, used for dyeing human hair | WELLA AG (DE) | 2003-08-05 | — | — | US | claimed |
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | claimed |
| US-20030070241-A1 | Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-04-17 | — | — | US | claimed |
| EP-1108708-B1 | 1,4-Diaminobenzene derivatives and colouring agents containing these compounds | WELLA AG (DE) | 2003-01-08 | — | — | EP | claimed |
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-12-19 | — | — | US | claimed |
| US-6436152-B1 | Substituted 2-aminoalky-1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | claimed |
| EP-1116711-A2 | 2-aminoalkyl-1,4-diaminobenzene derivatives and dye composition containing these compounds | Wella Aktiengesellschaft (DE) | 2001-07-18 | — | — | EP | claimed |
| EP-1108708-A1 | 1,4-Diaminobenzene derivatives and colouring agents containing these compounds | Wella Aktiengesellschaft (DE) | 2001-06-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, CYP1B1, ALDH7A1 | MAPT 3205/4885KDM4E 747/4885MEN1 2328/4885 |
| US-20030070241-A1 | Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, ALDH7A1, DDC | MAPT 3672/4885KDM4E 1141/4885MEN1 2231/4885 |
| US-20050081312-A1 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | KRT18, F12, HCN3 | MAPT 1861/4885KDM4E 3189/4885MEN1 3207/4885 |
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | KRT18, AOC1, DAO | MAPT 2345/4885KDM4E 1123/4885MEN1 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.