Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218130 | 1.00 | HTR2A (0.50) | HTR2AHTR2CMTNR1AMTNR1BPOLB | |
| Hydrochloric Acid SCHEMBL29171809 | 0.99 | HTR2A (0.49) | HTR2AHTR2CMTNR1AMTNR1BPOLB | |
| SCHEMBL31188804 | 0.91 | HTR2A (0.50) | HTR2AHTR2CMTNR1AMTNR1BPOLB | |
| SCHEMBL24734850 | 0.91 | HTR2A (0.50) | HTR2AHTR2CMTNR1AMTNR1BPOLB | |
| Hydrochloric Acid SCHEMBL29171816 | 0.90 | POLB (0.49) | HTR2AHTR2CMTNR1AMTNR1BPOLB | |
| Hydrochloric Acid SCHEMBL30861220 | 0.90 | POLB (0.49) | HTR2AHTR2CMTNR1AMTNR1BPOLB | |
| SCHEMBL24733403 | 0.87 | HTR2A (0.60) | HTR2AHTR2CMTNR1AMTNR1BMEN1 | |
| SCHEMBL24733587 | 0.83 | HTR2A (0.55) | HTR2AHTR2CPOLBMEN1MAPT | |
| SCHEMBL30277338 | 0.83 | HTR2A (0.55) | HTR2AHTR2CPOLBMEN1MAPT | |
| SCHEMBL31614532 | 0.83 | PKM (0.45) | HTR2APKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500487-A | Dimethoxy phenyl alkylamine activators of serotonin receptors | 恩泰奥吉尼克斯生物科学公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. | 2023-05-04 | — | — | US | disclosed |
| WO-2022261240-A2 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Life Sciences AG (DE) | 2022-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR1A, HTR7, HTR4 | HTR2A 12/4885HTR2C 8/4885MTNR1A 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.