SCHEMBL24734966

SCHEMBL24734966

Oc1ccc(/C=C2\c3ccccc3-c3ccc(-c4cc(-c5ccc6c(c5)/C(=C/c5ccc(O)cc5)c5ccccc5-6)cc(-c5ccc6c(c5)/C(=C/c5ccc(O)cc5)c5ccccc5-6)c4)cc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 2/20 0.44
RET P07949 1/20 0.44
FLT3 P36888 1/20 0.44
PLK4 O00444 1/20 0.44
PDGFRB P09619 1/20 0.44
CYP19A1 P11511 1/20 0.43
CYP11B2 P19099 1/20 0.43
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
AR P10275 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43
TUBB4B P68371 1/20 0.43
TUBB3 Q13509 1/20 0.43
TUBB2A Q13885 1/20 0.43
TUBB8 Q3ZCM7 1/20 0.43
TUBA3E Q6PEY2 1/20 0.43
TUBA1A Q71U36 1/20 0.43
TUBA1C Q9BQE3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24243656 0.83 PLK1 (0.33) PLK1RETFLT3PLK4PDGFRB
SCHEMBL24243655 0.77 ALDH1A1 (0.45) RETCYP19A1CYP11B2MEN1KMT2A
SCHEMBL26216364 0.75 MGLL (0.42) PLK1PLK4CYP19A1CYP11B2TUBB4A
SCHEMBL27282612 0.74 ESR2 (0.42) TUBB4ATUBBTUBA3CARTUBA1B
SCHEMBL26208936 0.74 GSTP1 (0.46) CYP1A2
SCHEMBL24243602 0.74 PTGS2 (0.48) CYP19A1CYP11B2MEN1KMT2ACYP1A2
SCHEMBL1225662 0.73 CYP19A1 (0.57) RETCYP19A1CYP11B2MEN1KMT2A
SCHEMBL7987352 0.71 LCK (0.47) PLK1RETFLT3PLK4PDGFRB
SCHEMBL4170410 0.70 MIF (0.56) CYP19A1CYP26A1MIF
SCHEMBL4170407 0.70 MIF (0.56) CYP19A1CYP26A1MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022172551-A1 LAMINATE, LAYER-FORMING COMPOSITION, LAYER, METHOD FOR MANUFACTURING LAMINATE, AND ELECTRONIC ELEMENT JSR株式会社 2022-08-18 WO disclosed