Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26844163 | 0.86 | USP2 (0.43) | ACACBGAAMAPTMAPK1HTT | |
| SCHEMBL26792083 | 0.82 | CDK1 (0.40) | HRH3ACACBMCOLN2RORC | |
| SCHEMBL25150431 | 0.82 | HIF1A (0.43) | KDM4EGAAMAPTMAPK1HTT | |
| SCHEMBL25453972 | 0.82 | HTR6 (0.44) | HTR6HRH4HRH3VCPHTR2B | |
| SCHEMBL24595076 | 0.81 | HIF1A (0.46) | KDM4EGAAMAPTMAPK1HTT | |
| SCHEMBL1704676 | 0.80 | MEN1 (0.43) | HTR6PDE7AVCPHTR2BPIM1 | |
| SCHEMBL14924024 | 0.80 | HTR3A (0.51) | HRH4KDM4EGAAMAPTMAPK1 | |
| SCHEMBL21725441 | 0.79 | BPTF (0.58) | HRH4PIM1CDK4CDK6ACACB | |
| SCHEMBL20883686 | 0.78 | ADRB1 (0.51) | HTR6HRH4HTR2BCDK4CDK6 | |
| SCHEMBL21024660 | 0.78 | LGMN (0.45) | KDM4EGAAMAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022245061-A1 | BENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING SAME AS ACTIVE INGREDIENT | 에이치케이이노엔 주식회사 | 2022-11-24 | — | — | WO | disclosed |