Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705135 | 0.74 | TSHR (0.35) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL8067905 | 0.69 | BCHE (0.46) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL20155546 | 0.68 | LMNA (0.43) | LMNACTSVCTSLCTSBCTSS | |
| SCHEMBL24736757 | 0.68 | TSHR (0.43) | LMNATSHRTACR1MMP2MMP3 | |
| SCHEMBL2578931 | 0.68 | PSEN1 (0.33) | LMNACTSVCTSLCTSBCTSS | |
| SCHEMBL22129891 | 0.68 | AKT1 (0.42) | LMNACTSVCTSLCTSBCTSS | |
| SCHEMBL25297066 | 0.67 | PSEN1 (0.39) | LMNACTSVCTSLCTSBCTSS | |
| SCHEMBL22091470 | 0.67 | PSEN1 (0.39) | LMNACTSVCTSLCTSBCTSS | |
| SCHEMBL21562481 | 0.66 | CTSV (0.40) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL10438674 | 0.66 | PDE4D (0.39) | TSHRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221514-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | GILEAD SCIENCES, INC. (US) | 2022-10-20 | — | — | WO | disclosed |