SCHEMBL24739634

SCHEMBL24739634

CO[Si](CCNc1ccc(Oc2cc3c4c(cc(Oc5ccc(NCC[Si](OC)(OC)OC)cc5)c5c6c(Oc7ccc(NCC[Si](OC)(OC)OC)cc7)cc7c8c(cc(Oc9ccc(NCC[Si](OC)(OC)OC)cc9)c(c2c45)c86)C(=O)N(C(C(=O)O)C(C)C)C7=O)C(=O)N(C(C(=O)O)C(C)C)C3=O)cc1)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.35
TP53 P04637 2/20 0.33
BRD4 O60885 3/20 0.33
MCL1 Q07820 1/20 0.33
LMNA P02545 1/20 0.32
RPS6KA2 Q15349 1/20 0.31
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 1/20 0.31
P2RX3 P56373 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24739948 0.87 FPR1 (0.41) TP53LMNAMAPT
SCHEMBL24740737 0.87 CTSK (0.33) CTSKTP53LMNACTSLCTSS
SCHEMBL24739613 0.80 SMN1; SMN2 (0.36) TP53LMNA
SCHEMBL24705016 0.77 CTSK (0.39) CTSKTP53LMNAL3MBTL1MAPT
SCHEMBL24739616 0.77 LMNA (0.46) TP53LMNAL3MBTL1MAPT
SCHEMBL24908715 0.76 DNMT1 (0.39) TP53MCL1
SCHEMBL24739685 0.76 SMN1; SMN2 (0.40) TP53LMNAMAPT
SCHEMBL24739623 0.75 LMNA (0.30) LMNA
SCHEMBL24739791 0.74 CNR2 (0.32) TP53LMNA
SCHEMBL24705029 0.74 ALDH1A1 (0.41) CTSKTP53MCL1LMNACTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220390841-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2022-12-08 US disclosed