SCHEMBL2474013

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3835157	0.85	GAA (0.51)	ROCK2KDM4EGAAKMT2AALDH1A1
	SCHEMBL2475721	0.83	HDAC1 (0.53)	ROCK2KDM4EGAAHDAC1HDAC6
	SCHEMBL2475158	0.78	HDAC1 (0.57)	HDAC1HDAC6HDAC3HDAC2HDAC4
	SCHEMBL2477479	0.77	HDAC1 (0.53)	ROCK2HDAC1HDAC6HDAC3HDAC2
	SCHEMBL3837475	0.76	HDAC1 (0.47)	ALDH1A1HDAC1HDAC6HDAC3HDAC2
	SCHEMBL1482531	0.75	RXRB (0.56)	ROCK2KDM4EGAAMEN1KMT2A
	SCHEMBL2384024	0.75	HDAC1 (0.49)	ROCK2KDM4EGAASMN1; SMN2HDAC1
	SCHEMBL1497030	0.74	ROCK2 (0.43)	ROCK2KDM4EGAASMN1; SMN2HDAC1
	SCHEMBL9784395	0.73	HDAC6 (0.72)	ALDH1A1HDAC1HDAC6HDAC3HDAC2
	SCHEMBL28966158	0.73	HDAC6 (0.80)	ALDH1A1HDAC1HDAC6HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.