Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265304 | 0.76 | — | — | |
| SCHEMBL24718638 | 0.76 | LTA4H (0.33) | KMT2ALTA4H | |
| SCHEMBL24717530 | 0.76 | LTA4H (0.33) | KMT2ALTA4H | |
| SCHEMBL10191534 | 0.73 | LTA4H (0.34) | LTA4H | |
| SCHEMBL8374122 | 0.71 | LMNA (0.46) | HRH3 | |
| SCHEMBL24740666 | 0.71 | HTR6 (0.31) | LTA4H | |
| SCHEMBL18099726 | 0.69 | FYN (0.33) | LTA4H | |
| SCHEMBL17947428 | 0.69 | FYN (0.33) | LTA4H | |
| SCHEMBL12716816 | 0.67 | FYN (0.35) | LTA4HHRH3 | |
| SCHEMBL22055072 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261120-A1 | nSMASE2 INHIBITOR PRODRUGS WITH ENHANCED ORAL AND BRAIN EXPOSURES | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-12-15 | — | — | WO | disclosed |