SCHEMBL2474112

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8004867	0.91	OPRM1 (0.50)	TSHROPRM1OPRD1NAMPTALDH1A1
	SCHEMBL2475852	0.89	OPRM1 (0.53)	TSHROPRM1OPRD1HDAC1HDAC3
	SCHEMBL4233246	0.89	TSHR (0.50)	TSHROPRM1OPRD1HDAC1ALDH1A1
	SCHEMBL2473469	0.88	HDAC1 (0.61)	TSHROPRM1OPRD1HDAC1HDAC3
	SCHEMBL2477227	0.88	OPRM1 (0.52)	TSHROPRM1OPRD1HDAC1HDAC3
	SCHEMBL2477106	0.88	OPRM1 (0.54)	TSHROPRM1OPRD1HDAC1HDAC3
	SCHEMBL2478140	0.87	HSD17B10 (0.52)	TSHROPRM1OPRD1HDAC1HDAC3
	SCHEMBL4222624	0.87	TSHR (0.47)	TSHROPRM1OPRD1HDAC1HDAC3
	SCHEMBL2476586	0.86	HSD17B10 (0.55)	TSHROPRM1OPRD1HDAC1HDAC3
	SCHEMBL2470965	0.86	OPRM1 (0.53)	TSHROPRM1OPRD1HDAC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.