Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602019 | 0.85 | TDP1 (0.58) | TDP1MAPK1EPHX2GAAPDK2 | |
| 1-Hydroxy-4-Isopentoxybenzene SCHEMBL2843554 | 0.83 | TDP1 (0.66) | TDP1MAPK1EPHX2GAAMGAM | |
| SCHEMBL7619788 | 0.82 | KDM4E (0.61) | TDP1MAPK1PDK2RAB9ANPC1 | |
| SCHEMBL9146689 | 0.81 | NPC1 (0.44) | TDP1GAAADRB2RAB9ANPC1 | |
| SCHEMBL9146695 | 0.81 | NPC1 (0.44) | TDP1GAAADRB2RAB9ANPC1 | |
| 1-Hydroxy-3-Isopentoxybenzene SCHEMBL2850085 | 0.81 | CHRNB2 (0.60) | TDP1MAPK1EPHX2PDK2 | |
| SCHEMBL9704804 | 0.80 | LTA4H (0.61) | GAARAB9ANPC1MEN1KMT2A | |
| SCHEMBL8956159 | 0.80 | LTA4H (0.61) | TDP1MAPK1GAARAB9ANPC1 | |
| SCHEMBL4090434 | 0.79 | TDP1 (0.51) | TDP1MAPK1EPHX2PDK2MMP2 | |
| SCHEMBL2562275 | 0.79 | TDP1 (0.47) | TDP1MAPK1EPHX2GAAPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220388997-A1 | COMPOUNDS FOR MODULATING ACTIVITY OF FXR AND USES THEREOF | GANNEX PHARMA CO., LTD. (CN) | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220388997-A1 | COMPOUNDS FOR MODULATING ACTIVITY OF FXR AND USES THEREOF | NR1H4, FXR1, FXR2 | TDP1 4815/4885MAPK1 1217/4885EPHX2 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.